A broad range, 100X concentrated, ready-to-use protease inhibitor cocktail, Mammalian ProteaseArrest™ inhibits mammalian serine, cysteine and other mammalian specific proteases including aminopeptidases, trypsin-like and aspartic proteases.
- Mammalian specific protease inhibitor cocktail
- 100X concentrated, ready-to-use solution
An optional EDTA solution is provided for enhanced metalloprotease inhibition. It is not present in the actual Mammalian ProteaseArrest™ cocktail as it would inhibit the activity of proteins that require divalent cations (Ca²⁺, Mg²⁺ or Mn²⁺) for their biological activity. In addition, EDTA will inhibit the purification of proteins using immobilised metal affinity chromatography.
Applications include inhibition of protease activity in protein preparations of mammalian lysates and protection of proteins from proteolysis in such applications as electrophoresis, purification, storage and assays.