HiScreen™ Capto™ MMC columns are prepacked with Capto™ MMC ion exchange chromatography medium. Capto™ MMC is a multimodal cation exchanger with a different selectivity compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges. The columns are an excellent choice for method optimisation and parameter screening.
- Prepacked, ready-to-use columns for convenient process development optimisation
- Small bed volume gives fast results and minimal sample/buffer consumption
- Easily connected in series to achieve 20 cm bed height
- Reproducible results, scalable to BioProcess columns packed with the same media using the same linear fluid velocity
The small column volume of 4,7 ml and bed height of 10 cm make HiScreen™ columns excellent tools for method optimisation, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, since the 10 cm bed height gives enough residence time and the results can then serve as basis for linear process scale-up.