Anti-CD86 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: GL-1]

Lieferant: Tonbo Biosciences

20-0862-U025EA 47.3 EUR
20-0862-U025 20-0862-U100
Anti-CD86 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: GL-1]
Antikörper
The GL-1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. 

Type: Primary
Antigen: CD86 (CD86 molecule)
Clonality: monoclonal
Clone: GL-1
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Rat
Isotype: IgG2a Kappa
Reactivity: Mouse
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