Anti-CD28 Mouse Monoclonal Antibody (FITC (Fluorescein)) [clone: CD28.2]

Lieferant: Tonbo Biosciences

35-0289-T025EA 43.6 EUR
35-0289-T025 35-0289-T100
Anti-CD28 Mouse Monoclonal Antibody (FITC (Fluorescein)) [clone: CD28.2]
Antikörper
The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

Type: Primary
Antigen: CD28 (CD28 molecule)
Clonality: monoclonal
Clone: CD28.2
Conjugation: FITC (Fluorescein)
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity:
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