Anti-CD80 Armenian Hamster Monoclonal Antibody (FITC (Fluorescein)) [clone: 16-10A1]

Lieferant: Tonbo Biosciences

35-0801-U100EA 68.6 EUR
35-0801-U100 35-0801-U025 35-0801-U500
Anti-CD80 Armenian Hamster Monoclonal Antibody (FITC (Fluorescein)) [clone: 16-10A1]
The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Type: Primary
Antigen: CD80 (CD80 molecule)
Clonality: monoclonal
Clone: 16-10A1
Conjugation: FITC (Fluorescein)
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse

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