Anti-IL2RA Rat Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: PC61.5]

Lieferant: Tonbo Biosciences

60-0251-U100EA 55.6 EUR
60-0251-U100 60-0251-U025
Anti-IL2RA Rat Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: PC61.5]
Antikörper
The PC61.5 antibody is specific for mouse CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Expression of CD25 varies during developmental stages of T and B cells, is induced on activated mature T and B cells, and is present on subsets of dendritic cells. CD25 signaling as part of the IL-2 receptor complex triggers T cell activation and proliferation, as well as modulating the differentiation and function of Th17 cells, T regulatory (Treg) cells, and dendritic cells.

Type: Primary
Antigen: IL2RA (interleukin 2 receptor, alpha)
Clonality: monoclonal
Clone: PC61.5
Conjugation: PE (Phycoerythrin)/Cy7®
Epitope:
Host: Rat
Isotype: IgG1 Lambda
Reactivity: Mouse
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