Anti-CD3E Mouse Monoclonal Antibody (violetFluor® 450) [clone: OKT3]

Lieferant: Tonbo Biosciences

75-0037-T025EA 53.8 EUR
75-0037-T025 75-0037-T100
Anti-CD3E Mouse Monoclonal Antibody (violetFluor® 450) [clone: OKT3]
Antikörper
The OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Type: Primary
Antigen: CD3E (CD3e molecule, epsilon (CD3-TCR complex))
Clonality: monoclonal
Clone: OKT3
Conjugation: violetFluor® 450
Epitope:
Host: Mouse
Isotype: IgG2a Kappa
Reactivity:
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