Anti-CD4 Rat Monoclonal Antibody (violetFluor® 450) [clone: GK1.5]

Lieferant: Tonbo Biosciences

75-0041-U025EA 56.5 EUR
75-0041-U025 75-0041-U100
Anti-CD4 Rat Monoclonal Antibody (violetFluor® 450) [clone: GK1.5]
Antikörper
The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

Type: Primary
Antigen: CD4 (CD4 molecule)
Clonality: monoclonal
Clone: GK1.5
Conjugation: violetFluor® 450
Epitope:
Host: Rat
Isotype: IgG2b Kappa
Reactivity:
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