Anti-4E-BP1 Mouse Monoclonal Antibody [clone: 9E12D9]

Lieferant: Thermo Fisher Scientific
PIEAMA515312EA 0 EUR
PIEAMA515312
Anti-4E-BP1 Mouse Monoclonal Antibody [clone: 9E12D9]
Antikörper
MA5-15312 targets 4E-BP1 in WB applications and shows reactivity with Human samples. The MA5-15312 immunogen is purified recombinant fragment of 4EBP1 expressed in E. Coli. This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Type: Primary
Antigen: 4E-BP1
Clonality: Monoclonal
Clone: 9E12D9
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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