Anti-IKBKB Mouse Monoclonal Antibody [clone: 10A2C5B3]

Lieferant: Thermo Fisher Scientific
PIEAMA515320EA 0 EUR
PIEAMA515320
Anti-IKBKB Mouse Monoclonal Antibody [clone: 10A2C5B3]
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MA5-15320 targets IKBKB in IHC and WB applications and shows reactivity with Human samples. The MA5-15320 immunogen is purified recombinant fragment of IKBKB expressed in E. Coli. NFKB1 or NFKB2 is bound to REL to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime .

Type: Primary
Antigen: IKBKB
Clonality: Monoclonal
Clone: 10A2C5B3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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