Meine Sitzung geöffnet lassen?
Endet in 
Ihre Sitzung ist abgelaufen
Ihre Sitzung ist abgelaufen. Zu Ihrer Sicherheit haben wir Sie abgemeldet.
Möchten Sie sich wieder anmelden?

Anti-HER2 Mouse Monoclonal Antibody [clone: 9B9D8]

Lieferant: Thermo Scientific
MA5-15332 targets HER-2 in IHC and WB applications and shows reactivity with Human samples. The MA5-15332 immunogen is purified recombinant fragment of HER-2 expressed in E. Coli. This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Type: Primary
Antigen: HER2
Clonality: Monoclonal
Clone: 9B9D8
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2b
Reactivity: Human



Erweitert / Kompakt
Größe VE Katalognummer Menge
100 µL 100 µl PIEAMA515332 Blocked
Blocked Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Generate Barcodes Barcode Label Format: 
PDF Katalogseiten erstellen


Antigen symbol HER2
Antigen name Receptor tyrosine-protein kinase erbB-2
Reaktivität Human
Konjugation Unconjugated
Klonalität Monoclonal
Antikörper Typ Primary
Clone 9B9D8
Host Mouse
Isotype IgG2b
Western blot Yes
ImmunoChemistry Yes
Antigen synonyms Receptor tyrosine-protein kinase erbB-2, CD340, metas, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, herstatin, c-erb B2/neu protein, p185erbB2, NEU, MLN 19, Tyrosine kinase-type cell surface receptor HER2, NGL, MLN19, Metastatic lymph node gene 19 protein
Gene ID 2064
Format ascites
Immunogen Purified recombinant fragment of HER-2 expressed in E. Coli.
Form Liquid
Storage buffer ascites, 0.03% sodium azide
Lagertemperatur Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Transporttemperatur Ice
Enter Details

Wählen Sie den Artikel dessen Zertifikat Sie gesucht haben

Chargennummer ist ein Pflichtfeld. Falls Sie diese nicht zur Verfügung haben, tragen Sie "x" für VWR Chemikalien ein.

Enter Certificate Details

Enter the Lot number:

Choose from recent batch/lot numbers:

Review & Compare Alternatives
We found alternative products that can save you up to  per item-unit.  To compare product details, select up to 3 alternatives below and click Compare Selected. To add items to your basket, enter a quantity and click Add to Basket.

Original Product:

Beschreibung Artikelnummer Availability Einheit Ihr Preis Price Per Menge