Anti-XRCC3 Rabbit Polyclonal Antibody

Lieferant: Thermo Fisher Scientific
PIEAPA116535EA 0 EUR
PIEAPA116535
Anti-XRCC3 Rabbit Polyclonal Antibody
Antikörper
This antibody is specific for XRCC3; no cross-reactivity was observed with XRCC2, RAD51, RAD51B, RAD51C, or RAD51D. This antibody is not recommended for ICC/IF applications. Suggested positive control: antigen standard for XRCC3 (transient overexpression lysate), TK6 lysates and 100 ug HeLa lysates. Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homolgs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes. XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination.

Type: Primary
Antigen: XRCC3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR