GPx-P belongs to the glutathione peroxidase family which are responsible for the detoxification of hydrogen peroxide. It protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. GPx-P is secreted in plasma and exists as a homotetramer.
This antibody has been shown to be specific for glutathione peroxidase 3 protein (GPx-P) through staining and blocking studies.
Application Information:
IHC, only. A dilution o f 1: 1000 to 1: 5000 is recommended for immunohistochemistry depending on detection method but end user will need to determine dilution to suit application. Antigen retrieval is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: glutathione peroxidase 3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: amino acids 135-154 of Human glutathione peroxidase 3 (GPx-P)
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat