FUNCTION: Receptor for the glial cell line-derived neurotrophic factor, artemin. Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase (By similarity). SUBCELLULAR LOCATION: Cell membrane; lipid-anchor; GPI-anchor (By similarity). SIMILARITY: Belongs to the GDNFR family.
Western blot analysis indicates a high level of specificity to GFR alpha-3 for this antiserum.
Application Information:
IHC, WB. A dilution of 1:500 to 1:1000 is recommended for both applications. This antibody stains nicely large neurons in the rat DRG. Specifically, if you would like to perform WB using rat brain homogenate detecting GFR alpha-3, this is the antibody to be used. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: GFR alpha-3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Mouse GFR alpha-3 protein (aa: 1-11)
Host: Rabbit
Isotype: IgG
Reactivity: Rat