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Anti-DVL1 Rabbit Polyclonal Antibody

Lieferant: ProSci Inc.
DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. Three transcript variants encoding three different isoforms have been found for this gene.

DVL1 antibody can be used for detection of DVL1 by ELISA at 1:62500. DVL1 antibody can be used for detection of DVL1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Antibody is purified by protein A chromatography method.

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type:
Antigen: DVL1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human




 

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Erweitert / Kompakt
Größe VE Katalognummer Menge
100 µg 100 µG PRSI27-500
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TECHNISCHE DATEN

Antigen symbol DVL1
Antigen name Dishevelled dsh homolog 1
Reaktivität Human
Konjugation Unconjugated
Klonalität Polyclonal
Wirt Rabbit
Western blot Yes
ELISA Yes
Antigen synonyms DRS2, DVL1L1, DVL, DVL1P1
Immunogen A synthetic peptide corresponding a region of human DVL1.
Form Lyophilized
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