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Anti-E2F6 Rabbit Polyclonal Antibody

Lieferant: ProSci Inc.
E2F6 is a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants encoding several different isoforms have been found for this gene.

E2F6 antibody can be used for detection of E2F6 by ELISA at 1:1562500. E2F6 antibody can be used for detection of E2F6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Antibody is purified by protein A chromatography method.

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type:
Antigen: E2F6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Dog, Human, Mouse, Rat




 

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Erweitert / Kompakt
Größe VE Katalognummer Menge
100 µg 100 µG PRSI27-522
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TECHNISCHE DATEN

Antigen symbol E2F6
Antigen name E2F transcription Factor 6
Reaktivität Mouse, Rat, Dog, Human
Konjugation Unconjugated
Klonalität Polyclonal
Wirt Rabbit
Western blot Yes
ELISA Yes
Antigen synonyms E2F6_HUMAN., E2F binding site modulating activity protein, MGC111545, E2F transcription factor 6, E2F 6, Transcription factor E2F6, EMA, E2F transcription factor 6 isoform 1
Immunogen A synthetic peptide corresponding a region of human E2F6.
Form Lyophilized
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