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Anti-RORC Rabbit Polyclonal Antibody

Lieferant: ProSci Inc.
RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

RORC antibody can be used for detection of RORC by ELISA at 1:1562500. RORC antibody can be used for detection of RORC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Antibody is purified by peptide affinity chromatography method.

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type:
Antigen: RORC
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human




 

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Erweitert / Kompakt
Größe VE Katalognummer Menge
50 µg 50 µG PRSI27-811
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TECHNISCHE DATEN

Antigen symbol RORC
Antigen name Retinoid related orphan receptor gamma
Reaktivität Human
Konjugation Unconjugated
Klonalität Polyclonal
Wirt Rabbit
Western blot Yes
ELISA Yes
Antigen synonyms RZRG, RORG, TOR, RZR-GAMMA, NR1F3
Immunogen A synthetic peptide corresponding a region of human RORC.
Form Lyophilized
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