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Anti-MST1R Rabbit Polyclonal Antibody

Lieferant: ProSci Inc.
MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers.

MST1R antibody can be used in immunohistochemistry starting at 20 μg/mL.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type:
Antigen: MST1R
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Gibbon, Human




 

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Erweitert / Kompakt
Größe VE Katalognummer Menge
50 µg 50 µG PRSI48-320
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TECHNISCHE DATEN

Antigen symbol MST1R
Antigen name Macrophage Stimulating 1 Receptor
Reaktivität Human, Gibbon
Konjugation Unconjugated
Klonalität Polyclonal
Wirt Rabbit
ELISA Yes
ImmunoChemistry Yes
Antigen synonyms p185-Ron, CD136, RON variant E2E3, MSP receptor, RON, CDw136, c-met-related tyrosine kinase, PTK8 protein tyrosine kinase 8, soluble RON variant 2, PTK8, soluble RON variant 3, soluble R, soluble RON variant 1, MST1R variant RON30, macrophage-stimulating protein receptor, MST1R variant RON62
Immunogen MST1R antibody was raised against a peptide located near the internal domain of MST1R (Human).
Form Liquid
Tested applications Immunoaffinity Chromatography
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