[Ala286]-CaM kinase II (281-302)

Lieferant: Enzo Life Sciences
ALEXBML-P202-0500EA 254 EUR
[Ala286]-CaM kinase II (281-302)
Proteine und Peptide
CaM kinase inhibitor

Sequence is from Ca²⁺/calmodulin-dependent protein kinase II autophosphorylation site within the pseudosubstrate negative regulatory region. Inhibition of CaMKII is as effective as BML-P201 (IC50=2 µM) but kinetics are not complicated by phosphorylation of the peptide by CaMKII itself because of the mutation of Thr286 to Ala.

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