Vincristinsulfat ≥98%

Lieferant: Enzo Life Sciences

ALEXBML-T117-0005EA 199 EUR
ALEXBML-T117-0005 ALEXBML-T117-0025
Vincristinsulfat ≥98%
Vincristine sulphate

Microtubule inhibitor


Plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Depolymerizes microtubules and blocks binding of tubulin to microtubule proteins. Causes aberrant tubulin polymerization. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent. Posttranscriptionally downregulates HIF-1α expression.

Formel: C₄₆H₅₈N₄O₁₄S
Molekulargewicht: 923,04 g/mol
MDL Number: MFCD00084729
CAS-Nummer: 2068-78-2
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