These columns are designed for separating highly hydrophilic molecules by hydrophilic interaction liquid chromatography (HILIC). They are suited for use in a broad range of applications, including separation of hydrophilic drugs and drug metabolites.
- Retention of highly polar molecules that are not retained by reversed-phase chromatography
- Unique selectivity, complementary to reversed-phase columns
- Hydrolytically stable
The advantage of the Acclaim™ HILIC-10 phase is the compatibility with up to 20% aqueous mobile phase, while maintaining affinity for polar analytes.
Particle type: high purity, spherical, porous silica
Flow rate range: 0,8 to 1,6 ml/min for 4,6 mm ID formats; 0,4 to 0,8 ml/min for 3,0 mm ID formats; 0,2 to 0,4 ml/min for 2,1 mm ID formats